What is LPV?
Lysine-Proline-Valine (LPV) is a bioactive tripeptide studied for anti-inflammatory and immunomodulatory properties.
It is structurally related to KPV and investigated for roles in cytokine suppression and epithelial repair.
Structure
Peptide Name: Lysine-Proline-Valine
Synonym: LPV
Sequence: Lys-Pro-Val
Molecular Formula: C₁₆H₃₀N₄O₅
Molecular Weight: ~358.4 g/mol
Research
1. Inflammatory Modulation
LPV has shown the ability to downregulate pro-inflammatory cytokines in cellular models.
2. Barrier Tissue Support
Studied for protective effects in gut and epithelial lining research.
3. Immune Signaling
May influence macrophage and neutrophil response pathways.
Future Research
Ongoing work explores dermatologic applications, gastrointestinal inflammation models, and peptide stability optimization.
Resources
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Tripeptide cytokine modulation studies
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Epithelial repair peptide research
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Comparative KPV/LPV anti-inflammatory models


Reviews
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