GHK-Cu 50mg

What is GHK-Cu?

GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It has been extensively researched for its roles in tissue remodelling, wound healing, anti-inflammatory signalling, and gene expression regulation.

GHK-Cu Structure

GHK-Cu Research

1. GHK-Cu and Wound Healing

Multiple studies have demonstrated that GHK-Cu accelerates wound closure, promotes collagen synthesis, and enhances angiogenesis in tissue repair models.

2. GHK-Cu and Gene Regulation

Microarray studies have revealed that GHK-Cu modulates the expression of over 4,000 genes, including upregulation of anti-inflammatory, antioxidant, and repair-associated pathways.

3. GHK-Cu and Antioxidant Defense

GHK-Cu has been shown to upregulate superoxide dismutase and catalase expression, contributing to cellular antioxidant defense in oxidative stress models.

Future GHK-Cu Research

Emerging research is investigating GHK-Cu in neurodegeneration models, pulmonary fibrosis, and oncology, given its broad gene-regulatory profile.

GHK-Cu Resources

• Pickart L, Margolina A. – Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci, 2018.
• Pickart L. – The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed, 2008.