Sermorelin 10mg

SKU: SML10

Sermorelin 10mg – GHRH analog peptide for growth hormone research.

Price range: $75.00 through $180.00

Packaging

Description

What is Sermorelin?

Sermorelin (GHRH 1–29 NH₂) is a synthetic analog of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). It acts on the pituitary gland to stimulate the release of endogenous growth hormone, and is extensively studied in models of GH deficiency and aging-associated GH decline.

Sermorelin Structure

Peptide Name	Sermorelin
Synonyms	GHRH(1-29), GRF(1-29)NH2
Sequence	Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Molecular Formula	C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular Weight	3,357.9 g/mol

Sermorelin Research

1. Sermorelin and GH Secretion

Sermorelin binds to GHRH receptors (GHRHR) on somatotroph cells of the anterior pituitary, stimulating pulsatile GH release. Research models confirm dose-dependent GH elevations following Sermorelin administration.

2. Sermorelin and Body Composition

Studies in GH-deficient animal models demonstrate that Sermorelin-induced GH release promotes lean mass preservation and fat mass reduction, relevant to metabolic and aging research.

3. Sermorelin and Aging

Research into GH axis restoration during aging has utilised Sermorelin as a model compound, with results showing improved IGF-1 levels, bone density markers, and sleep architecture in aged subjects.

Future Sermorelin Research

Future investigations are exploring Sermorelin in pediatric GH deficiency models, age-related sarcopenia, and combination protocols with GHRPs for enhanced GH pulse amplitude.

Sermorelin Resources

Walker RF. – Sermorelin: A better approach to management of adult-onset growth hormone insufficiency? Clin Interv Aging, 2006.
Corpas E, et al. – Human growth hormone and human aging. Endocrine Reviews, 1993.