Kisspeptin-10 10mg

SKU: KS10

Kisspeptin-10 10mg – neuropeptide research compound involved in reproductive endocrinology and GnRH signalling.

Price range: $95.00 through $228.00

Packaging

Description

What is Kisspeptin-10?

Kisspeptin-10 is a truncated 10-amino-acid fragment of the kisspeptin family of neuropeptides, encoded by the KISS1 gene. It is a key regulator of the hypothalamic–pituitary–gonadal (HPG) axis, acting as a potent stimulator of gonadotropin-releasing hormone (GnRH) secretion in research models.

Kisspeptin-10 Structure

Peptide Name	Kisspeptin-10
Synonyms	KP-10, metastin (45–54)
Sequence	Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Molecular Formula	C₆₃H₈₃N₁₅O₁₃
Molecular Weight	1,302.44 g/mol

Kisspeptin-10 Research

1. Kisspeptin-10 and GnRH Signalling

Kisspeptin-10 binds to KISS1R (GPR54) receptors on GnRH neurons, triggering robust LH and FSH surges in animal and human research models.

2. Kisspeptin-10 and Testosterone Regulation

Studies have shown that Kisspeptin-10 administration leads to measurable increases in LH pulse frequency, modulating testosterone secretion in male subjects in controlled research settings.

3. Kisspeptin-10 and Metabolic Interplay

Emerging research suggests Kisspeptin signalling intersects with energy homeostasis, with KISS1R expressed in peripheral metabolic tissues including the pancreas and adipose tissue.

Future Kisspeptin-10 Research

Future research directions include its role in puberty timing, fertility regulation, and potential applications in hypogonadism research models.

Kisspeptin-10 Resources

Dhillo WS, et al. – Kisspeptin-54 stimulates the hypothalamic–pituitary gonadal axis. J Clin Endocrinol Metab, 2005.
Oakley AE, et al. – Kisspeptin signaling in the brain. Endocrine Reviews, 2009.